Brain: Tests and treatments for Psychological problems

There are a number of rarely recognized causes and treatments for some psychological problems.

Psychiatric illnesses can be caused by “poisoning” from too much acetaldehyde (AH) in the body from Candida, Yeasts, and Molds. Nutrients can help remove AH and clear up the brain difficulties from this. See Appendix 2

ADHD: Can be caused by hard-to-detect food sensitivities. Food sensitivity panels provide valuable practical information. Adherence to an allergen-free diet can, in some cases , dramatically decrease or resolve these behaviors. There are many other considerations to help these individuals, including removing food additives, sulfites and adding fish oil and other restorative products for brain functioning. Because of the close connection between brain and gut function, it is important to evaluate this connection as well.

Chronic brain low-grade inflammation from “bugs” can convert too much tryptophan (from serotonin antidepressants)  into a brain toxins (quinolones) and cause an atypical “serotonin syndrome.” Learn how to overcome this problem.

Schizoid and Schizophrenia: These individuals can have excessive methyl-dopamines and other toxic breakdown products of catecholamines. Learn how to use nutrients to protect the brain from these toxic products–And help improve their function.

Many psychiatric illnesses can be caused by Kryptopyrroles.   See Appendix 1   Once this diagnosis is documented, a specific vitamin and mineral protocol rapidly resolves this condition.

Biotoxins from chronic microbes can cause memory loss, “brain fog,” diminished “multi-tasking,” headaches and other brain deficits. Learn how to overcome this problem.

MHPG: A natural breakdown product of norepinephrine, whose levels are low in autism and related disorders involving the brain. Naturals and/or medicinals can help. See Appendix 3

Early memory loss: There are intense  nutritional interventions that can show dramatic improvements. See page on Early Memory Loss

Appendix 1 

Kryptopyrroles, Pyrrole Disorder and Pyroluria

If you have this condition, you will have a dramatic improvement with nutrients.

The symptoms vary but may include:

  • lack of dream recall
  • white spots on nails
  • dislikes loud noises or bright lights
  • problems with menstrual cycle or sex problems
  • problems with depression
  • pale skin, skin that easily burns
  • insomnia
  • stunted growth, late growth spurt
  • prone to temper outbursts
  • likes spicy foods
  • better long-term than short-term memory
  • reading difficulties
  • ADHD (Attention Deficit Hyperactivity Disorder) symptoms
  • anemia (low iron)
  • protruding abdomen
  • delayed pubertyIn severe cases other disorders may be present as well such as: OCD (Obsessive-Compulsive Disorder), Bipolar Disorder, severe depression, Tourette Syndrome, Schizophrenia, Autism, and others.

The Pyroluria Test will tell you if you have elevated pyrroles which are inhibiting vitamin B6, zinc and biotin from doing the many roles required of them for your body. A referral for testing of this condition and restoration of key vitamins that are deficient can resolve this problem.

Appendix 2 Acetaldehyde (AH) and the effects on the brain and body systems

  • A partial summary of AHs damaging effects on brain function includes the following:
  • Impaired memory
  • Brain fog (decreased concentration)
  • Depression
  • Lethargy and apathy
  • Irritability
  • Increase in anxiety and panic reactions

Appendix 3 :

MHPG (3 methoxy-4-hydroxyphenylglycol) is a natural breakdown product of a

class of neurotransmitters called catecholamines. One of the catecholamine

neurotransmitters that is broken down to MHPG is norepinephrine (NE). Since

the 1970s, the urine of autistic children has been known to contain abnormally

low amounts of MHPG (Young, J.G. et al., Decreased 24-Hour Urinary MHPG

in Childhood Autism. Am J.Psychiatry 136, August 1979, pp. 1055-7).

In order for the body to get rid of MHPG, it has to convert it, in a process called

“conjugation”, either to MHPG sulfate or MHPG glucuronide—the two pathways

referenced above.

By measuring the amount of MHPG sulfate, MHPG glucuronide, and total

MHPG (the sum of the sulfate and the glucuronide) excreted in the urine in

24 hours, we can find out two things:

1. The turnover rate of the catecholamine neurotransmitters, especially NE,

in the body. It is the use (i.e., the release) of NE that leads to the breakdown of

NE to MHPG. Low total urinary excretion of MHPG suggests that smaller than

normal amounts of NE are being released into the synapses of the brain.

(Young, J.G., et al. Cerebrospinal Fluid, Plasma, and Urinary MHPG in

Children, Life Sciences, Vol. 28, 1981, pp. 2837-45) and Peyrin, L, Urinary

MHPG Sulfate as a Marker of Central Norepinephrine Metabolism: A

Commentary, J. Neural Trans [Gen.Sect], Vol. 80, 2990, pp.51-65) C.

Barthelemy and Associates found this was accompanied with higher than normal

levels of NE in the urine—J Autism Dev Disord, 1988 Dec, 18:4, 583-91. These

findings suggest that autistic behaviors might be related to an abnormal functional

imbalance among monoamines either at a molecular level or at a system level.

2. The relative efficiency of the two main conjugation pathways for MHPG

(and by extension, for other phenolic compounds, such as salicylates and artificial

food colors):  sulfoconjugation and glucuronidation.

If needed, you can strengthen the effect of the glucuronidation by supplying

calcium-d-glucarate. The calcium-d-glucarate prevents the bacteria in the intestine

from removing the glucuronides that were conjugated with (attached to) the toxins.

When the bacteria remove the glucuronides, the now unconjugated toxins can be

reabsorbed from the gut back into the body. Wilner’s Chemists carries

calcium-d-glucarate. High doses of vitamin C may increase

the glucuronidation pathway activity.

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